Single cell RNA sequencing reveals functionally validated signatures of cytotoxicity in anti-FRá CoStimulatory Antigen Receptor (CoStAR™) activated CD4+ T cells. Post date November 4, 2023 ← A CD28/CD40 based chimeric costimulatory antigen receptor (CoStAR™) targeting folate receptor alpha enhances anti-tumour activity of tumour infiltrating lymphocytes → Anti-folate receptor alpha (FRα) CoStimulatory Antigen Receptor (CoStAR™) drives distinct cytokine-mediated proliferation responses in CD4+ and CD8+ T cells.
Instil Bio